Medicine Description glivec 400mg
Glivec 400mg Tablets is a medication that functions primarily as a tyrosine kinase inhibitor. It specifically targets and inhibits the activity of the BCR-ABL fusion protein, which is an abnormal enzyme produced by the Philadelphia chromosome, commonly associated with chronic myeloid leukemia (CML). By blocking this enzyme, Glivec disrupts the signaling pathways that promote the proliferation and survival of cancer cells, leading to reduced tumor growth and progression. Additionally, Glivec is effective against other tyrosine kinases involved in gastrointestinal stromal tumors (GISTs), thereby restricting the growth of these tumors as well. This targeted approach helps minimize damage to normal cells, making it a preferred choice for patients with specific malignancies.
Indications and Uses of Glivec 400mg Tablets
- Chronic Myeloid Leukemia (CML) in the chronic phase
- Gastrointestinal Stromal Tumors (GISTs) that are unresectable or metastatic
- Acute Lymphoblastic Leukemia (ALL) with the Philadelphia chromosome
- Hypereosinophilia and/or systemic mastocytosis
Side Effects of Glivec 400mg Tablets
- Fatigue
- Nausea
- Fluid retention
- Rash
- Muscle cramps
- Diarrhea
Storage and Handling
Store Glivec 400mg Tablets at room temperature, away from moisture and heat. Ensure that the medication is kept out of reach of children and is not used after the expiration date on the package.
Patient Advice and Precautions
Patients should take Glivec consistently as prescribed and attend regular follow-up appointments for blood tests to monitor treatment response and side effects. It's essential to report any unusual symptoms, such as severe abdominal pain or unexplained bleeding, to a healthcare provider immediately. Avoid self-medication and do not stop taking Glivec without consulting a healthcare professional. Patients should also be aware of potential drug interactions and discuss all medications they are taking with their doctor.