Medicine Description glivec 100mg
Glivec 100mg Capsule is a medication that primarily targets and inhibits the activity of specific tyrosine kinases, particularly BCR-ABL, which is produced by the Philadelphia chromosome in chronic myeloid leukemia (CML). By blocking this enzyme's function, Glivec disrupts the signaling pathways that promote cell proliferation and survival in cancerous cells. This targeted approach significantly reduces the growth of malignant cells while sparing normal ones, leading to improved outcomes in patients with certain types of cancer.
Indications and Uses of Glivec 100mg Capsule
- Chronic Myeloid Leukemia (CML) in the chronic phase
- Gastrointestinal Stromal Tumors (GIST) that are unresectable or metastatic
- Acute Lymphoblastic Leukemia (ALL) with Philadelphia chromosome positivity
- Myelodysplastic/Myeloproliferative Diseases associated with eosinophilia and rearrangement of the PDGFRB gene
Side Effects of Glivec 100mg Capsule
- Nausea
- Vomiting
- Fatigue
- Fluid retention
- Rash
- Muscle cramps
- Abdominal pain
- Elevated liver enzymes
Storage and Handling
Store Glivec capsules at room temperature, away from excessive heat and moisture. Keep out of reach of children and ensure the medication is stored in its original packaging to protect from light.
Patient Advice and Precautions
Patients should adhere to their prescribed treatment regimen and attend regular follow-up appointments for monitoring. It's important to report any unusual symptoms or side effects to a healthcare provider promptly. Patients should also be aware of potential interactions with other medications and should discuss all concurrent treatments with their healthcare professional.