Tasigna
Tasigna
|
scientific Name |
Nilotinib hcl 200 mg.
|
|
Dosage | 200mg
|
|
Type | Capsule
|
| Status |
In stock |
Price: 1,387.20 SAR | SAR
Medicine Description tasigna 200mg
Indication For the potential treatment of various leukemias, including chronic myeloid leukemia (CML). Pharmacodynamics Nilotinib is a transduction inhibitor that targets BCR-ABL, c-kit and PDGF, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML). Mechanism of action Chronic myelogenous leukaemia (CML) is caused by the BCR-ABL oncogene. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. Nilotinib fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib, over-riding resistance caused by mutations. The ability of AMN107 to inhibit TEL-platelet-derived growth factor receptor-beta (TEL-PDGFRbeta), which causes chronic myelomonocytic leukaemia, and FIP1-like-1-PDGFRalpha, which causes hypereosinophilic syndrome, suggests potential use of AMN107 for myeloproliferative diseases characterised by these kinase fusions (Stover et al, 2005- Weisberg et al, 2005). AMN107 also inhibits the c-Kit receptor k
the price tasigna 200mg Capsule in saudi arabia |
1,387.20 SAR |
the price tasigna 200mg Capsule in uae |
1,387.20 AED |
the price tasigna 200mg Capsule in kuwait |
113.29 KWD |
the price tasigna 200mg Capsule in oman |
138.72 OMR |
the price tasigna 200mg Capsule in Bahrain |
138.72 BHD |