About Nandrolone An anabolic steroid, Erythropoietic. Mechanism of Action of Nandrolone It is an anabolic steroid which have higher anabolic and lower androgenic activity. It is a synthetic testosterone derivative which have anabolic androgenic ratio >1.It binds with cytoplasmic testosterone receptors in androgen responsive organs and tissues and forms hormone receptor complex. This hormone-receptor complex binds with DNA and enhances DNA transcription and formation of mRNA which ultimately leads to modification of protein synthesis. It exerts anabolic effect on skeleton and skeletal muscles and also accelerates erythropoiesis. The drug accelerates erythropoiesis by elevating the levels of hormone erythropoietin involved in the production of red blood cells. It maintains positive nitrogen balance. It reverses corticosteroid induced catabolism and promotes tissue development. Due to androgenic action it exerts inhibitory effects on hormone responsive breast tumors and metastases.