Other Indications & Uses Beta-lactamase-producing: S. aureus, E. coli, Klebsiella spp, P. mirabilis, Bacteroides fragilis, Enterobacter spp, Acinetobacter calcoaceticus Systemic Adverse Reactions systemic reactions reported in less than 1% of the patients were: itching, nausea, vomiting, candidiasis, fatigue, malaise, headache, chest pain, flatulence, abdominal distension, glossitis, urine retention, dysuria, edema, facial swelling, erythema, chills, tightness in throat, substernal pain, epistaxis and mucosal bleeding.