Activase vial is used to help dissolve acute blood clots. It contains alteplase, a substance that activates the
breakdown of clots inside blood vessels. It is used in emergency conditions such as heart attacks, ischemic strokes,
and certain cases of pulmonary embolism.
It helps improve blood flow and reduce complications caused by vascular blockage. It is administered in hospitals
under strict medical supervision due to the need for continuous monitoring during treatment. It is considered an
important drug for rapid intervention in life-threatening clot-related conditions.
Composition of Activase
Activase contains the following active ingredient:
Strength and dosage form of Activase
Activase is available as a vial in a 50 mg strength, containing 29 million international units. The package contains 2
vials. It is used under strict medical supervision in cases requiring thrombolytic therapy, according to the
specialist’s assessment.
Indications for use of ACTIVASE
The main uses of Activase include:
Treatment of acute myocardial infarction (heart attack).
Treatment of ischemic stroke caused by blood clots.
Treatment of acute pulmonary embolism.
Dissolving intravascular blood clots.
Improving blood flow and reducing complications.
Emergency hospital use in critical conditions.
Reducing tissue damage caused by arterial blockage.
Dosage of Activase
The drug is administered via intravenous injection only. The dose varies depending on the type of clot and the
patient’s condition. It is used exclusively in hospitals under specialized medical supervision.
Continuous monitoring of the patient is required throughout treatment to ensure safety and response. The dose must not
be modified or adjusted without consulting the physician.
Side effects of Activase
The most common side effects of Activase include:
Contraindications of Activase
Activase should not be used in cases of active bleeding or a history of brain hemorrhage. It is also contraindicated
in patients with severe clotting disorders or recent surgery.
Extreme caution is required in patients with uncontrolled hypertension or liver disease. It should only be used under
full medical supervision in specialized hospital settings.
Alternatives to Activase in pharmacies
Available alternatives include:
Actilyse.
Alteplase.
Reteplase.
Tenecteplase.
Proper use of Activase
This medication is used only in hospitals under specialist supervision. Vital signs must be continuously monitored
throughout treatment, and the prescribed dose must be strictly followed without any changes.
Patients must be closely observed for any signs of bleeding, and any unusual symptoms should be reported immediately.
It must never be used outside medical supervision due to serious risks.
Storage conditions
It should be stored under the following conditions:
Store at a temperature as recommended by the manufacturer.
Keep away from direct light.
Do not freeze.
Keep in the original packaging.
Keep out of reach of children.