Asenapine sublingual tablets are used as an antipsychotic medication for the treatment of certain psychiatric
disorders such as schizophrenia and bipolar disorder. They work by helping to restore the balance of natural chemicals
in the brain, which improves mood, thinking, and behavior.
It is characterized by rapid absorption because it is taken sublingually, where it is absorbed directly into the
bloodstream without passing through the full digestive process. It helps reduce episodes of agitation, delusional
thoughts, and hallucinations.
Composition of Asenapine
Asenapine contains the following active ingredient:
Strength and dosage forms of Asenapine
This medication is available in several forms and strengths, including sublingual tablets of 2.5 mg, 5 mg, and 10 mg.
It is also available in packs containing 30 tablets. The appropriate strength is selected according to the condition
under medical supervision.
Indications for use of ASENAPINE-HIKMA
The main uses of Asenapine include:
Treatment of schizophrenia.
Treatment of bipolar disorder.
Reduction of hallucinations and abnormal thoughts.
Control of manic episodes.
Improvement of overall mood stability.
Dosage of Asenapine
The usual starting dose is 2.5 mg twice daily, with gradual adjustment depending on the patient’s response under
medical supervision. The dose prescribed by the physician should not be exceeded.
The tablet must be placed under the tongue until it completely dissolves to ensure optimal absorption.
Side effects of Asenapine
The most common side effects of Asenapine include:
Drowsiness and fatigue.
Mild dizziness.
Weight gain.
Dry mouth.
Changes in appetite.
Contraindications of Asenapine
Asenapine should not be used in cases of allergy to the active ingredient or in patients with severe heart problems or
low blood pressure. It should not be used without medical supervision in elderly patients with dementia. Caution is
required during pregnancy, breastfeeding, and in complex psychiatric conditions.
Alternatives to Asenapine in pharmacies
Available alternatives include:
Risperidone.
Olanzapine.
Quetiapine.
Aripiprazole.
Use during pregnancy and breastfeeding
Asenapine should be used with caution during pregnancy and breastfeeding and only when necessary under strict medical
supervision. The expected benefits should be carefully weighed against potential risks before starting treatment.
The mother’s condition should be regularly monitored during use. Breastfeeding is generally not recommended during
treatment unless advised by a physician.
Storage conditions
It should be stored under the following conditions:
Store at a temperature below 30°C.
Keep away from moisture and heat.
Keep in a tightly closed container.
Keep out of reach of children.