Cidogen Cream is an effective dermatological preparation specifically designed to treat a wide range of fungal infections affecting the superficial layers of the skin. This cream contains the active ingredient Isoconazole Nitrate at a concentration of 1%, a compound that belongs to a class of drugs known as azole antifungals. This class of drugs works by interfering with the basic biological processes of fungi, inhibiting their growth and ultimately eliminating them, thus effectively and safely treating fungal skin infections. Cidogen Cream is a reliable treatment option for relieving the symptoms associated with fungal infections and restoring skin health.
The active ingredient in Cidogen Cream
The therapeutic efficacy of Cidogen Cream depends entirely on the presence of the following active ingredient at a precise concentration:
Isoconazole Nitrate: 1% w/w. This concentration means that every 100 grams of cream contains 1 gram of isoconazole nitrate, which is an ideal amount to achieve a strong, topical therapeutic effect against common skin fungi.
Mechanism of Action of Cidogen Cream
Isoconazole nitrate exerts its antifungal effect by targeting a vital process essential to fungal growth and reproduction: ergosterol synthesis. Ergosterol is a vital component necessary for building and maintaining the structural and functional integrity of the fungal cell membrane. The mechanism of action of isoconazole nitrate includes:
Cytochrome P450 inhibition: Isoconazole inhibits the activity of a specific enzyme belonging to the cytochrome P450 family, an enzyme essential for fungi to produce ergosterol.
Ergosterol deficiency: As a result of inhibiting this enzyme, ergosterol production in fungal cells is significantly reduced.
Fungal cell membrane disturbance: Ergosterol deficiency leads to structural and functional changes in the fungal cell membrane, increasing its permeability and disrupting vital functions such as nutrient transport, waste disposal, and maintaining cell homeostasis.
Growth inhibition and death: This disruption of the fungal cell membrane ultimately inhibits fungal growth, prevents fungal reproduction, and ultimately leads to fungal death, eliminating the fungal infection in the skin.
Indications for use of Cidogen Cream
Cidogen 1% Cream is used effectively to treat a wide range of superficial fungal skin infections caused by various types of fungi, including:
Tinea Pedis or Athlete's Foot: A common fungal infection of the skin of the feet, especially between the toes, characterized by itching, redness, scaling, and cracking.
Tinea Corporis or Ringworm: A fungal infection of the skin of the body that appears as red, circular or ring-shaped patches with a raised border.
Tinea cruris (or jock itch): A fungal infection of the groin and genital area characterized by itching, redness, and a rash.
Tinea versicolor: A superficial fungal infection that causes small, discolored patches (light or dark) on the chest, back, and arms. It is caused by the fungus Malassezia furfur.
Cutaneous candidiasis: A fungal infection of the skin and mucous membranes caused by the fungus Candida, characterized by redness, itching, and a white discharge.