Amaryl M is a combination drug that is essential in the treatment of type 2 diabetes, a chronic condition characterized by high blood sugar levels resulting from impaired insulin secretion and tissue resistance to its action. This drug contains a dual formulation of two active ingredients that work through two different yet complementary mechanisms to lower blood sugar levels: glimepiride and metformin. This combination provides more comprehensive blood sugar control than either drug alone, making it an effective treatment option for patients who are unable to achieve their blood sugar treatment goals with a single drug. Amaryl M helps improve the quality of life for patients with type 2 diabetes and reduce the risk of complications associated with long-term hyperglycemia.
Active Ingredients in Amaryl M
The therapeutic efficacy of Amaryl M depends on the synergistic effect of the following two active ingredients at their specified concentrations in the tablet:
Glimepiride: Glimepiride belongs to the third-generation sulfonylurea class. It primarily works by stimulating the beta cells in the islets of Langerhans in the pancreas to secrete more insulin in response to blood glucose levels.
Metformin: Metformin belongs to the biguanide class. It works by reducing glucose production in the liver and increasing the sensitivity of peripheral tissues, especially muscles, to insulin. This increases glucose uptake from the blood and its use as an energy source. It also reduces glucose absorption from the intestine.
Amaryl M is a key combination drug in the treatment plans of patients with type 2 diabetes, a chronic condition characterized by high blood glucose levels resulting from impaired insulin secretion and tissue resistance to its action. This medication contains a dual formulation of two active ingredients that work in two different, complementary ways to lower blood sugar levels: glimepiride and metformin. This combination provides more comprehensive blood sugar control than either drug alone, making it an effective treatment option for patients who cannot achieve their blood sugar treatment goals with a single drug. Amaryl M helps improve the quality of life for patients with type 2 diabetes and reduce the risk of complications associated with long-term hyperglycemia.
Amaryl M strengths available on the market
Amaryl M is available in various strengths of glimepiride with metformin to meet various treatment needs. Common strengths available on the market include:
Glimepiride 1 mg / Metformin 500 mg: Typically used as a starting dose or for patients requiring less controlled blood sugar. Glimepiride 2 mg / Metformin 500 mg: This is a commonly used strength for most patients requiring moderate blood sugar control.
Glimepiride 4 mg / Metformin 500 mg: This is used for patients requiring tighter blood sugar control and may be appropriate for patients who have not responded adequately to lower strengths.
Other metformin formulations with different strengths may also be available in some markets. Your doctor will determine the appropriate strength and dose based on a comprehensive assessment of your condition, blood sugar levels, response to treatment, and other risk factors. It is important to follow your doctor's instructions carefully regarding dosage and timing.