Mechanism of Action of Biotin Biotin excerts it`s pharmacological action by influencing metabolic reactions. It acts as a coenzyme for carbohydrate, fat, and protein metabolism. It is required for cell growth and production of fatty acids. It is required for healthy maintenance of hair, skin, sweat glands, nerve tissue, and bone marrow. It also helps in the transfer of carbon dioxide and in the maintenance of a steady blood sugar level. Indications for Biotin 1.Biotin deficiency 2 Alopecia 3.Brittle nails 4.Prevent diabetic neuropathy and lower blood glucose levels in diabetic patients 5.Seborrheic dermatitis 6.Dry skin. Typical Dosage for Biotin Oral: 30 to 70mcg daily. Increased up to 300mcg/day if required based on the severity of deficiency. Pregnancy: 30mcg daily Lactation: 35mcg daily Prevent brittle nails: 2.5mg/day.