Comtan tablets are mainly used in the treatment of Parkinson disease. The drug works by inhibiting an enzyme known as catechol-O-methyltransferase (COMT), which is the enzyme responsible for breaking down dopamine in the brain. Through this mechanism, Comtan helps improve dopamine levels in the brain, which contributes to alleviating symptoms of the disease such as stiffness, slow movement, and tremors.
Comtan is often given with other medications to enhance their effect and reduce episodes of stopping or sudden decrease in the effectiveness of the drug. It is recommended to use it under close medical supervision to ensure a balance between its benefits and possible side effects.