About Tranexamic Acid Lysine Analog, Hemostatic, competitive plasminogen activationinhibitor, Antifibrinolytic,Antihemophilic. Mechanism of Action of Tranexamic Acid Tranexamic acid exerts antifibrinolytic effect by forming a reversible complex with plasminogen through the lysine binding site of fibrin and thus displaces the plasminogen from the fibrin surface - preventing the binding of plasmin to fibrinogen or fibrin monomers. It inhibits the activation of plasminogen (i.e. formation of plasmin). It also acts as a weak non competitive inhibitor of plasmin and blocks it`s action on fibrin. Indications for Tranexamic Acid 1.Surgical procedures 2.Menorrhagia 3. Metrorrhagia 4.Post partum haemorrhage 5.Haemorrhage after abortion 6.Haemorrhage due to contraceptive device insertion 7.Tooth extractions and haemorrhage in other dental procedures 8.Epistaxis 9.Haemoptysis 10.Gastrointestinal bleeding 11.Prostatectomy 12.Tonsillectomy 13.Fibrinolysis