Medicine Description domperidone 60mg
Domperidone 60 mg tablets is a medication that primarily acts as a dopamine D2 receptor antagonist. By blocking these receptors in the gastrointestinal tract, it enhances the peristaltic movement of the stomach and the intestines, facilitating the passage of food. Furthermore, it reduces the likelihood of nausea and vomiting by inhibiting dopaminergic signaling in the chemoreceptor trigger zone of the central nervous system. This dual action helps improve gastric emptying and alleviates discomfort associated with delayed gastric motility.
Indications and Uses of Domperidone 60 mg tablets
- Management of symptoms associated with gastroparesis.
- Relief of nausea and vomiting due to various causes.
- Improvement of gastric emptying in patients with delayed gastric emptying.
- Adjunctive treatment for certain patients with chronic dyspepsia.
Side Effects of Domperidone 60 mg tablets
- Dry mouth
- Abdominal cramps
- Diarrhea
- Dizziness
- Headache
- Fatigue
- Rarely, extrapyramidal symptoms or arrhythmias
Storage and Handling
Store Domperidone 60 mg tablets in a cool, dry place away from direct sunlight. Keep out of reach of children and ensure that it is stored in its original packaging to maintain its efficacy.
Patient Advice and Precautions
Patients should be advised to inform their healthcare provider of any existing medical conditions, particularly those involving the heart or liver. It is essential to discuss all medications currently being taken to avoid potential interactions. Domperidone should be used cautiously in individuals with a history of arrhythmias or electrolyte imbalances.