About Ginseng Steroid glycosides. Mechanism of Action of Ginseng It contains chemicals called ginsenosides that seem to affect insulin levels in the body and lower blood sugar. Other chemicals, called polysaccharides, might affect the immune system. Indications for Ginseng 1.Adaptogen-adapt to internal/external stressors, fight fatigue, increase stamina 2.Lowering blood sugar after a meal in people with type 2 diabetes 3.Preventing respiratory tract infections such as the common cold or influenza in adults Interactions for Ginseng 1.Warfarin:Ginseng decreases its effectiveness. 2.Medications for diabetes (Antidiabetes drugs). 3.Antidepressants: Panax ginseng might stimulate the body.. Taking Panax ginseng with these medications used for depression might cause too much stimulation. This might cause side effects such as anxiousness, headache, restlessness, and insomnia.