Medicine Description protam 10 mg
Protam injection is a medication that counteracts the effects of heparin. It is used to treat cases of heparin overdose or toxicity and contains protamine sulfate, which works by neutralizing heparin action in the body.
What are the ingredients of Protam?
Protam consists of the following components:
- Each milliliter of the solution contains 10 milligrams of protamine sulfate, an active substance that acts as an antidote to heparin.
- It also contains inactive ingredients that help maintain the drug stability and ease of use without affecting its effectiveness.
Indications for using Protam
It is used to treat the following conditions:
- Treatment of heparin overdose
- Neutralizing the effect of heparin during surgical procedures
- Managing bleeding caused by heparin use
- After dialysis or open-heart surgery
- In cases of uncontrolled bleeding due to heparin
What are the dosages of Protam?
The dosage is determined based on the condition and includes:
- The dose depends on the amount, type, and method of heparin administration
- Typically, 1 milligram of protamine neutralizes 100 international units of heparin
- The dose should be administered slowly via intravenous injection over 10 minutes
- A single dose should not exceed 50 milligrams
- Coagulation tests should be monitored after administration
What are the side effects of Protam?
It may cause some symptoms, including:
- Low blood pressure
- Bradycardia (slow heart rate)
- Shortness of breath
- Nausea or vomiting
- Facial flushing or a feeling of warmth
- Pulmonary edema
- Severe allergic reactions that may be life-threatening