Nebilet tablets are a medication widely used to control high blood pressure and treat some cases of heart failure. These tablets contain the active ingredient nebivolol hydrochloride at a concentration of 5 mg. Nebivolol belongs to a class of medications called beta-blockers, and is characterized by its selective beta-1 receptor antagonism in the heart, in addition to its vasodilatory effect by stimulating nitric oxide production. This dual effect helps reduce heart rate and contraction force, and reduces vascular resistance, leading to lower blood pressure and improved heart function in cases of heart failure.
What are the ingredients in Nebilet?
Nebilet tablets contain the following active ingredient:
Nebivolol hydrochloride: 5 mg.
The tablets also contain inactive ingredients.
Indications for Use of Nebilet
Nebilet tablets are used to treat:
Essential hypertension: to lower high blood pressure in adults.
Chronic stable heart failure: as an adjunctive therapy in patients aged 70 years or older.
The goal of treatment is to lower blood pressure to normal levels, reduce the burden on the heart, and improve the quality of life of patients with these conditions.
What is the dosage of Nebilet?
Nebilet tablets should be taken as directed by your doctor. The dosage and duration of treatment depend on the patient's condition, the severity of the disease, and their response to the medication.
For high blood pressure: The usual starting dose is 5 mg once daily. The dose can be gradually adjusted after several weeks.
For heart failure: Start with a very low dose (such as 1.25 mg) and gradually increase it over time (usually one to two weeks) under close medical supervision until the effective or maximum tolerated dose is reached. The tablet should be swallowed whole with a glass of water. The medication can be taken with or without food, preferably at the same time each day. It is very important to adhere to the prescribed dose and not stop taking the medication suddenly, as abruptly stopping beta-blockers may worsen some heart conditions.
What are the side effects of Nebilet?
Nebilet tablets may cause some side effects, some of which are common and others can be serious:
Common side effects (especially at the beginning of treatment):
Headache.
Dizziness, fatigue.
Numbness or tingling in the hands and feet.
Shortness of breath.
Gastrointestinal disturbances: diarrhea or constipation, nausea.
Edema (swelling) in the extremities.
More serious or rare side effects:
Severely slow heart rate (bradycardia).
Severely low blood pressure.
Worsening of asthma or chronic obstructive pulmonary disease.
Heart failure (in rare cases or with incorrect dosages).
Liver problems (rare).
Severe allergic reactions.
Erectile dysfunction in men.
Notify your doctor immediately if you experience any severe, persistent, or unusual side effects, especially a very slow heartbeat, difficulty breathing, or severe swelling.