Risaldene tablets are an essential medication for the treatment and prevention of osteoporosis, a disease that affects bones and makes them fragile, weak, and more susceptible to fractures. This medication contains the active ingredient risedronate sodium, 35 mg per tablet. Risedronate sodium belongs to the bisphosphonate class of medications, a group of drugs that work to reduce the excessive activity of cells that break down bone, helping to maintain bone density and strength. Risaldene 35 mg is a suitable treatment option for weekly dosing, making it easier for patients to adhere to treatment and reducing the frequency of doses.
The active ingredient in Risaldene tablets
The therapeutic efficacy of Risaldene tablets depends primarily on the following active ingredient:
Risedronate sodium: 35 mg per tablet. Risedronate sodium is also available in other strengths, such as 5 mg for daily use or 150 mg for monthly use. The 35 mg strength is specifically designed for a weekly dosing schedule.
Mechanism of Action of Risaldene Tablets
Risedronate sodium works at the cellular level in the bone to reduce bone loss. Its primary mechanism of action is:
Binding to the bone surface: Risedronate sodium is absorbed after administration and selectively binds to the bone surface, particularly in areas where bone is actively broken down.
Osteoclast Inhibition: After binding to the bone, risedronate sodium inhibits the activity of the cells responsible for bone resorption and breakdown, called osteoclasts. It reduces the number, function, and ability of these cells to adhere to the bone surface.
Maintaining Bone Mass: By reducing osteoclast activity, the rate of bone breakdown slows, allowing osteoblasts a greater opportunity to build new bone. This helps maintain a healthy balance between bone building and bone breakdown, leading to the maintenance or increase of bone mass over time.
Increased bone strength: Increasing bone density improves bone strength and resistance to fractures, reducing the risk of fractures, especially in the spine, hip, and wrist, which are the most common sites of fractures resulting from osteoporosis.
Indications for using Risaldene tablets
Risaldene tablets are used to treat and prevent osteoporosis in a number of conditions determined by a doctor, including:
Treatment of osteoporosis in postmenopausal women: to increase bone mass and reduce the risk of spine, hip, and other fractures.
Prevention of osteoporosis in postmenopausal women: those at risk of developing the disease and who are not recommended for other treatments.
Treatment of osteoporosis in men: to increase bone mass and reduce the risk of fractures.
Treatment and prevention of osteoporosis resulting from corticosteroid use: in men and women who use systemic corticosteroids for long periods.