Comparison of the difference between Duphalac and Picolax syrup and which is better as laxative

19 April 2025

    Both Duphalac and Picolax are used to treat constipation, but they differ in the active ingredients they contain, their mechanism of action, and the time it takes for the effect to appear. Understanding these differences helps determine the most appropriate medication for constipation relief.

    Duphalac Syrup Ingredients

    Duphalac Syrup contains the active ingredient lactulose. Lactulose is a synthetic sugar that is not absorbed by the body. It acts as an osmotic laxative by increasing the amount of water in the large intestine, making stool softer and easier to pass. It also helps treat hepatic encephalopathy by reducing the production and absorption of ammonia in the intestine.

    Picolax Syrup Ingredients

    Picolax Syrup contains the active ingredient sodium picosulfate. Sodium picosulfate is a stimulant laxative. It works by stimulating intestinal movement (peristalsis), which helps push stool out of the body. It is activated in the large intestine by intestinal bacteria.

    Information about Duphalac Syrup

    Drug Class: Osmotic Laxatives

    Drug Classification: Sugars

    Pharmaceutical Form: Syrup

    Pharmaceutical Family: Gastrointestinal Drugs

    Active Ingredient: Lactulose

    Information about Picolax Syrup

    Drug Class: Stimulant Laxatives

    Drug Classification: Dihydroxyanthracene Derivatives

    Pharmaceutical Form: Syrup

    Pharmaceutical Family: Gastrointestinal Drugs

    Active Ingredient: Sodium Picosulfate


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