Medicine Description tarceva 150mg
Tarceva 150mg Tablets is a medication that functions as a selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. By binding to the ATP-binding site of EGFR, erlotinib prevents autophosphorylation and subsequent activation of signaling pathways involved in cell proliferation and survival. This inhibition disrupts crucial processes that contribute to the growth of cancer cells, particularly in tumors expressing mutated forms of EGFR, thereby impeding tumor growth and promoting apoptosis in susceptible cancer cells.
Indications and Uses of Tarceva 150mg Tablets
- Non-small cell lung cancer (NSCLC) with activating EGFR mutations.
- Pancreatic cancer in combination with gemcitabine.
Side Effects of Tarceva 150mg Tablets
- Skin rash and acneiform eruptions.
- Diarrhea.
- Fatigue.
- Loss of appetite.
- Nausea.
- Stomatitis (mouth sores).
- Interstitial lung disease (rare but serious).
Storage and Handling
Store Tarceva 150mg Tablets at room temperature, away from moisture and heat. Keep out of reach of children and do not use after the expiration date printed on the packaging.
Patient Advice and Precautions
Patients should be advised to report any skin reactions or respiratory symptoms promptly. It is important to avoid sun exposure and use sunscreen due to potential skin sensitivity. Regular monitoring of liver function tests is recommended, as liver toxicity can occur. Patients should also be counseled on the importance of adherence to the prescribed regimen and the potential need for supportive care to manage side effects.