Medicine Description leflumine 100mg
Leflumine 100 mg 3 tablets is a medication classified as a disease-modifying antirheumatic drug (DMARD). It works by inhibiting the enzyme dihydroorotate dehydrogenase, which is pivotal in the de novo synthesis pathway of pyrimidines. This action reduces the proliferation of activated lymphocytes, leading to decreased inflammation and a modulation of the immune response. Consequently, leflunomide effectively slows down the progression of autoimmune conditions, thereby alleviating symptoms such as pain, stiffness, and swelling associated with rheumatoid arthritis and other inflammatory arthropathies.
Indications and Uses of Leflumine 100 mg 3 tablets
- Management of rheumatoid arthritis in adults
- Treatment of active psoriatic arthritis
- Control of symptoms related to certain autoimmune disorders
- Possible use in other inflammatory conditions as determined by healthcare professionals
Side Effects of Leflumine 100 mg 3 tablets
- Diarrhea
- Nausea
- Abdominal pain
- Hair loss
- Rash
- Headache
- Increased liver enzymes
- Risk of infections due to immunosuppression
Storage and Handling
Store Leflumine tablets at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Do not use beyond the expiration date printed on the package.
Patient Advice and Precautions
It is essential to have regular check-ups to monitor liver function and blood cell counts while on leflunomide. Patients should be informed about the potential for serious side effects and the importance of adhering to follow-up appointments. Avoid pregnancy while taking this medication and consult your healthcare provider for any planned surgeries or dental work.