Medicine Description lomotil 2.5mg
Lomotil 2.5 mg tablets is a medication that combines diphenoxylate and atropine to manage diarrhea. Diphenoxylate, an opioid derivative, works by acting on the gut's mu-opioid receptors, which decreases peristalsis and increases the time it takes for gastrointestinal contents to pass, thereby reducing the frequency of bowel movements. Atropine, an anticholinergic agent, is included to deter misuse of diphenoxylate due to its potential for abuse. Atropine works by inhibiting the action of acetylcholine on muscarinic receptors, leading to reduced gastrointestinal motility and secretions, complementing the effects of diphenoxylate to effectively manage diarrhea.
Indications and Uses of Lomotil 2.5 mg tablets
- Management of acute nonspecific diarrhea
- Symptomatic relief of diarrhea associated with inflammatory bowel disease
- Adjunctive treatment for diarrhea caused by certain gastrointestinal disorders
Side Effects of Lomotil 2.5 mg tablets
- Drowsiness
- Dizziness
- Dry mouth
- Constipation
- Nausea
- Abdominal discomfort
Storage and Handling
Store Lomotil 2.5 mg tablets at room temperature, away from moisture and heat. Keep out of reach of children and do not use past the expiration date.
Patient Advice and Precautions
Patients should be advised to stay hydrated while using this medication. It is important to avoid alcohol and other central nervous system depressants, as they may increase drowsiness. Notify a healthcare provider if diarrhea persists for an extended period or if there is a presence of blood in the stool.