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- Arpimune ME 100mg
Arpimune ME 100mg
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- Scientific Name: Cyclosporine 100 mg
- Drag Period: once daily before meal
- Type: Capsule
- Producing Company: RPG-ÇÓÊíÑÇÏ ÇáãßÊÈ ÇáÊÌÇÑì ÇáÏæáì
Medicine Description
About Cyclosporin A A cyclic nonribosomal peptide(11 amino acids) immunosuppressant drug, Organ transplant rejection prevention. Mechanism of Action of Cyclosporin A Cyclosporine binds to the cytosolic protein cyclophilin (immunophilin) of immunocompetent lymphocytes, especially T-lymphocytes. This complex inhibits calcineurin, which is responsible for activating the transcription of interleukin 2. It also inhibits lymphokine production and interleukin release and therefore leads to reduced function of effecter T-cells. Drug prevents mitochondrial PT pore from opening and inhibits cytochrome C release and also apoptosis induced by it. Indications for Cyclosporin A 1. Organ transplant rejection 2. Rheumatoid arthritis 3. Crohn`s syndrome 4. Nephrotic syndrome 5. Psoriasis 6. Ulcerative colitis 7. Uveitis 8. Neuroprotection in traumatic brain injury 9. Aplastic anemia 10. Myasthenia gravis 11. Dermatomyositis
Price: 574 EGP.
Medicine Description
About Cyclosporin A A cyclic nonribosomal peptide(11 amino acids) immunosuppressant drug, Organ transplant rejection prevention. Mechanism of Action of Cyclosporin A Cyclosporine binds to the cytosolic protein cyclophilin (immunophilin) of immunocompetent lymphocytes, especially T-lymphocytes. This complex inhibits calcineurin, which is responsible for activating the transcription of interleukin 2. It also inhibits lymphokine production and interleukin release and therefore leads to reduced function of effecter T-cells. Drug prevents mitochondrial PT pore from opening and inhibits cytochrome C release and also apoptosis induced by it. Indications for Cyclosporin A 1. Organ transplant rejection 2. Rheumatoid arthritis 3. Crohn`s syndrome 4. Nephrotic syndrome 5. Psoriasis 6. Ulcerative colitis 7. Uveitis 8. Neuroprotection in traumatic brain injury 9. Aplastic anemia 10. Myasthenia gravis 11. Dermatomyositis
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