Medicine Description brufen-cream 10%
Brufen 10% Cream is a medication that contains ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID). It exerts its therapeutic effects by inhibiting the activity of cyclooxygenase enzymes (COX-1 and COX-2), which play a pivotal role in the conversion of arachidonic acid to prostaglandins. Prostaglandins are chemical messengers that promote inflammation, pain, and fever. By blocking these enzymes, ibuprofen reduces the synthesis of prostaglandins, leading to a decrease in inflammation, swelling, and pain at the site of application. This localized action makes topical ibuprofen effective for treating musculoskeletal pain while minimizing systemic exposure and associated side effects.
Indications and Uses of Brufen 10% Cream
- Localized pain relief from conditions such as muscle strains and joint sprains
- Management of acute back pain
- Alleviation of neck pain
- Symptomatic relief in rheumatoid arthritis and osteoarthritis
- Supportive therapy for sports injuries and overuse syndromes
Side Effects of Brufen 10% Cream
- Skin irritation at the application site
- Redness or rash
- Burning sensation
- Allergic reactions including itching or swelling
- Exacerbation of asthma symptoms in sensitive individuals
Storage and Handling
Store Brufen 10% Cream at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Do not freeze.
Patient Advice and Precautions
Ensure that the affected area is clean and dry before applying the cream. Avoid contact with eyes or mucous membranes. Wash hands after application unless treating hands. Do not use on broken or infected skin without consulting a healthcare professional. Discontinue use and seek medical advice if severe skin reactions occur.