About Miconazole An imidazole derivPeople began using tincture of iodine as a wound disinfectant in the late 1800s. Although not as popular today, it is still in use as an antiseptic to prevent infection in minor cuts, scrapes and burns. Tincture of iodine is suitable for topical use only and can be irritating to your skin. You should not use tincture of iodine on open wounds or if you are allergic to seafood.ative, Broad spectrum Antifungal. Mechanism of Action of Miconazole Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis Indications for Miconazole 1.Tinea versicolor 2.Vulvovaginal candidiasis 3.Tinea pedis 4.Tinea corporis 5.Tinea cruris 6.Otomycosis 7.Onychomycosis 8.Oral candidiasis 9.Intestinal candidiasis 10.Diaper dermatitis