Medicine Description votrient 200mg
Votrient tablets are an anticancer medicine containing pazopanib, which belongs to the tyrosine kinase inhibitor
class. It works by blocking signals that help cancer cells grow and form new blood vessels.
It is used to treat certain types of advanced cancer under the supervision of a specialist. It is particularly used in
some cases of kidney cancer and soft tissue sarcoma. The dose and treatment plan are determined according to the type
of tumor, the patient’s health condition, and response to treatment.
Votrient Ingredients
The medicine contains the following active ingredient:
Votrient Strengths
The medicine is available in the following strength:
Votrient Uses
The main uses of the medicine include:
Treatment of advanced renal cell carcinoma in some patients.
Treatment of certain cases of advanced or metastatic kidney cancer.
Treatment of certain cases of advanced soft tissue sarcoma.
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May be used after previous treatments in specific cases of soft tissue sarcoma according to the doctor’s
assessment.
Votrient Dosage
The doctor determines the appropriate dose according to the type of cancer, the patient’s health condition, and
tolerance to treatment. The usual adult dose for some indications is:
| Age |
Dose |
Frequency |
| Adults |
800 mg |
Once daily |
How to Use Votrient Correctly
The medicine should be used according to the treatment plan prescribed by the doctor. The following instructions are
recommended:
Take the dose at the same time every day.
Take the medicine on an empty stomach, at least 1 hour before food or at least 2 hours after food.
Swallow the tablet whole with a glass of water.
Do not crush, chew, or break the tablet.
Avoid grapefruit and grapefruit juice during treatment unless your doctor advises otherwise.
Do not take any other medicine without consulting your doctor or pharmacist.
Monitor blood pressure regularly during treatment.
Your doctor may request periodic liver function tests.
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Inform your doctor if you experience unusual bleeding, significant changes in vision, chest pain, or shortness of
breath.
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If you miss a dose, follow your doctor’s instructions and do not take a double dose to make up for the missed
dose.
Votrient Contraindications
The medicine should not be used in patients with a known allergy to pazopanib or any of the other ingredients. It
should also not be used without medical evaluation in patients with severe liver problems, heart conditions, or
uncontrolled high blood pressure.
The doctor should be informed about any history of bleeding, blood clots, thyroid disorders, or gastrointestinal
problems. The doctor should also be informed about all medicines and supplements being used because Votrient has
multiple potential drug interactions that may affect pazopanib levels or increase the risk of side effects.
Votrient Side Effects
The most common possible side effects include:
Diarrhea.
Nausea.
Vomiting.
Loss of appetite.
Changes in taste.
Tiredness and fatigue.
High blood pressure.
Headache.
Changes in hair color.
Changes in skin or nail color.
Weight loss.
Increased liver enzyme levels.
Muscle or joint pain.
Skin rash.
Changes in taste sensation.
Votrient Alternatives
The appropriate alternative can be selected according to the active ingredient, strength, and availability of the
product. Cancer treatment should not be replaced or changed without consulting the treating doctor.
Some mentioned alternatives include Balversa, Lorbrena, and Brukinsa. The suitability of any alternative must be
confirmed according to the patient’s condition and prescribed treatment plan.
Votrient Storage Conditions
The medicine should be stored under the following conditions:
Store at room temperature.
Keep away from excessive heat and moisture.
Keep inside the original package to protect it from moisture.
Keep out of the reach of children.
Do not use after the expiration date stated on the package.
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Do not dispose of the medicine in wastewater or household garbage. Ask your pharmacist about the appropriate way
to dispose of unused medicines.
Frequently Asked Questions
Can grapefruit be taken with Votrient?
It is recommended to avoid grapefruit and grapefruit juice while using Votrient because grapefruit may increase the
concentration of the medicine in the blood, which may increase the risk of side effects.
Does Votrient interact with other medicines?
Yes. Votrient has numerous potential drug interactions, and its effectiveness may be affected or the risk of side
effects may increase when it is used with certain medicines. Examples include some antibiotics, antifungal medicines,
HIV medicines, simvastatin, certain heart medicines, and some medicines that reduce stomach acidity.
What happens if I miss a dose of Votrient?
If you remember the missed dose and there are 12 hours or more until the next scheduled dose, you may take the missed
dose. If the next dose is due in less than 12 hours, skip the missed dose and continue treatment at the usual time.
How long does Votrient treatment last?
There is no fixed treatment duration. Votrient is generally continued until the disease stops responding to treatment,
significant toxicity occurs that requires treatment to be stopped or the dose to be adjusted, or the treating doctor
decides to discontinue therapy.