Medicine Description vokanamet 50/1000mg
Vokanamet is a combination medicine used to help control blood glucose levels in adults with type 2 diabetes.
Canagliflozin helps the kidneys eliminate more glucose through the urine, while metformin reduces glucose production
in the liver and improves the body's response to insulin.
Vokanamet Ingredients
The active ingredients are:
Canagliflozin.
Metformin Hydrochloride.
Vokanamet Available Strengths
The medicine is available in the following strengths:
50/850 mg tablets, 60 film-coated tablets.
50/1000 mg tablets, 60 film-coated tablets.
150/850 mg tablets, 60 film-coated tablets.
150/1000 mg tablets, 60 film-coated tablets.
Vokanamet Uses
The main uses of Vokanamet include:
Used when metformin alone is not sufficient to control blood glucose levels.
-
May be used with other glucose-lowering medicines when the previous treatment plan does not provide adequate
control.
-
May be used in patients who are already taking canagliflozin and metformin separately and need to replace them
with a single combination tablet.
Used together with an appropriate diet and regular physical activity.
Helps improve blood glucose control.
Vokanamet Dosage
The appropriate dose is determined by the doctor based on the patient's previous treatment, kidney function, and blood
glucose levels. Common prescribed doses may include:
| Age |
Dose |
Frequency |
| Adults |
150/1000 mg |
One tablet twice daily |
| Adults |
150/850 mg |
One tablet twice daily |
| Adults |
50/1000 mg |
One tablet twice daily |
| Adults |
50/850 mg |
One tablet twice daily |
How to Use Vokanamet Correctly
Use Vokanamet according to your doctor's instructions and follow these recommendations:
Take the tablet at the time specified by your doctor.
The medicine is usually taken twice daily according to the prescribed dose.
Take the doses with meals to help reduce stomach-related side effects associated with metformin.
Swallow the tablet whole with an adequate amount of water.
Do not crush or chew the tablet unless specifically instructed by your doctor.
Drink an adequate amount of fluids to help reduce the risk of dehydration.
Continue following the recommended diet and physical activity plan.
Monitor your blood glucose according to your doctor's instructions.
Do not stop the medicine or change the dose without consulting your doctor.
Contraindications for Vokanamet
Vokanamet should not be used in people with a known allergy to canagliflozin, metformin, or any of the other
ingredients. It is also contraindicated in diabetic ketoacidosis, diabetic pre-coma, and severe kidney impairment.
The medicine should be avoided in severe conditions that may affect kidney function, such as severe dehydration or
severe infection. It may also be unsuitable in severe liver impairment or certain conditions associated with reduced
oxygen supply to body tissues, such as severe heart or respiratory failure.
Tell your doctor if you consume large amounts of alcohol or have any medical condition that may increase the risk of
metformin-associated lactic acidosis.
Vokanamet Side Effects
Possible side effects may include:
Increased urination.
Increased thirst and dry mouth.
Low blood sugar, particularly when used with insulin or certain other diabetes medicines.
Genital fungal infections.
Urinary tract infections.
Nausea.
Diarrhea.
Weakness or dizziness.
Stomach and digestive disturbances, particularly at the beginning of treatment.
Dehydration and low blood pressure in some patients.
Vokanamet Alternatives
There are other medicines used to control blood glucose, including Janumet. However, Vokanamet should not be replaced
with another medicine without medical advice because differences in active ingredients or strengths may require
adjustment of the dose and treatment plan.
Storage Conditions
Store Vokanamet under the following conditions:
Keep at room temperature according to the instructions on the package.
Store in a dry place.
Keep away from moisture and excessive heat.
Protect from direct sunlight.
Keep in the original package until use.
Keep out of reach of children.
Do not use after the expiry date.
Frequently Asked Questions
Does Vokanamet cause fungal infections?
Yes. Vokanamet may increase the risk of fungal infections, particularly genital fungal infections, because it contains
canagliflozin, an SGLT2 inhibitor. This type of medicine increases the amount of glucose excreted in the urine, which
can create conditions that promote fungal growth.
Can Vokanamet be used during pregnancy?
Vokanamet is generally not recommended during pregnancy, particularly because it contains canagliflozin, for which
there is insufficient information regarding its safety during pregnancy. Consult your doctor if you are pregnant or
planning to become pregnant.
Can Vokanamet be used while breastfeeding?
Vokanamet is generally not recommended during breastfeeding because the safety of canagliflozin in breastfed infants
has not been established. Consult your doctor to determine the most appropriate treatment during breastfeeding.
Can Vokanamet be used with insulin?
In some cases, canagliflozin-containing diabetes medicines may be used together with insulin. However, combining them
may increase the risk of hypoglycemia, so your doctor may need to adjust the insulin dose and recommend regular blood
glucose monitoring.