Medicine Description vigam 5 %
Vigam is an immunoglobulin preparation that belongs to the class of immune globulins and immune sera. It contains the
active ingredient immunoglobulin, which helps strengthen the immune system and provides rapid protection against
infections.
It effectively replaces missing antibodies in patients with immunodeficiency, helps treat certain autoimmune diseases,
reduces inflammation of the nerves and blood vessels, and enhances the body's ability to fight microorganisms while
strengthening the immune response in both acute and chronic conditions.
Vigam Ingredients
The medication contains the following active ingredient:
Human normal immunoglobulin.
Vigam Strengths
Available in the following dosage forms and strengths:
• 5% solution for infusion, 50 mL vial.
• 5% solution for infusion, 100 mL vial.
• Vigam S 5% solution for infusion, 50 mL vial.
• Vigam S 5% solution for infusion, 100 mL vial.
Vigam Uses
The main indications include:
• Treatment of primary and secondary immunodeficiency disorders to provide protection against infections.
• Treatment of immune thrombocytopenia to help prevent bleeding.
• Treatment of Guillain-Barré syndrome and immune-mediated neuropathies.
• Treatment of Kawasaki disease in children to reduce the risk of coronary artery complications.
• Immune support following bone marrow or organ transplantation.
Vigam Dosage
The dosage is determined according to the patient's body weight and the condition being treated. It is prescribed
individually by the physician and administered as a slow intravenous infusion in a hospital or specialized medical
center. The infusion rate and dosing schedule are adjusted based on the patient's response and the results of clinical
assessments and laboratory tests.
How to Use Vigam Correctly
Use the medication only as directed by your physician and follow these recommendations:
• The medication must be administered only under the supervision of qualified healthcare professionals in a hospital
or medical center.
• Monitor the patient's vital signs throughout the intravenous infusion.
• Begin the infusion at a slow rate and increase it gradually according to the patient's tolerance.
• Ensure adequate hydration before the infusion by drinking sufficient fluids when appropriate.
• Stop the infusion immediately and inform the physician if symptoms such as difficulty breathing or signs of an
allergic reaction occur.
Contraindications
Do not use Vigam if you have a known hypersensitivity to immunoglobulin or any human plasma proteins.
It is also contraindicated in patients with IgA deficiency who have developed anti-IgA antibodies because of the risk
of severe anaphylactic reactions. Extra caution and close medical supervision are required in patients with kidney
failure, dehydration, or an increased risk of thromboembolic events.
Side Effects
The most common side effects include:
• Headache or a mild increase in body temperature during intravenous infusion.
• Chills or general fatigue.
• Nausea or mild back and joint pain.
• Temporary low or high blood pressure.
• Mild increase in heart rate or irritation at the injection site.
Vigam Alternatives
Available alternatives include Introglobin, Octagam, Qubrovix, and Ginemune. Do not replace Vigam with another product
without consulting your physician, as concentrations, formulations, and approved indications may differ.
Storage Conditions
Store under the following conditions:
• Store refrigerated at 2°C to 8°C.
• Do not freeze.
• Keep out of the reach of children.
• Keep the product in its original package to protect it from light.
Frequently Asked Questions
Should Vigam be stored in the refrigerator?
Yes. Vigam should be stored in a refrigerator at 2°C to 8°C and must not be frozen. Keep it in its original package
until use to protect it from light.
What are the main uses of Vigam in children?
Vigam is used in children with primary immunodeficiency and certain cases of secondary immunodeficiency. It may also
be used to treat specific autoimmune or inflammatory conditions in children as determined by the treating physician.
Does Vigam require monitoring during administration?
Yes. Vigam should be administered under medical supervision with continuous monitoring during and after the infusion,
especially during the first dose or when increasing the infusion rate, to detect and manage any allergic reactions or
adverse effects promptly.
What is the difference between Vigam and Vigam S?
The difference between Vigam and Vigam S may relate to the formulation, pharmaceutical presentation, or manufacturing
process, depending on the manufacturer. Both products contain human immunoglobulin and are used to treat
immunodeficiency disorders and certain immune-mediated diseases. The treating physician will determine the most
appropriate product based on the patient's condition and clinical needs.