Stelara contains ustekinumab, an immunomodulatory medication that helps regulate immune system activity in patients
with certain chronic inflammatory diseases.
It works by reducing excessive immune responses that may lead to symptoms affecting the skin, digestive system, or
joints.
The medication is used under specialist medical supervision as part of carefully planned treatment programs based on
the type and severity of the disease. It has a relatively long duration of action, allowing administration at extended
intervals according to the prescribed treatment schedule.
Composition of Stelara
Available Strengths and Pharmaceutical Forms
Vial containing 130 mg (5 mg/mL).
Prefilled syringe for subcutaneous injection: 45 mg/0.5 mL.
Prefilled syringe for subcutaneous injection: 90 mg/mL.
Indications for Stelara
Treatment of moderate to severe plaque psoriasis.
Treatment of psoriatic arthritis.
Treatment of Crohn’s disease in selected cases.
Treatment of ulcerative colitis according to physician assessment.
Helping control chronic immune-mediated inflammatory conditions.
Reducing symptoms associated with excessive immune system activity.
Dosage and Administration
The dosage varies depending on the disease being treated, the patient's health status, and body weight. The treating
physician determines the appropriate treatment regimen for each individual case.
In some situations, the initial dose may be administered by intravenous infusion in a healthcare facility. Subsequent
doses may then be given by subcutaneous injection according to the prescribed treatment schedule.
Patients should adhere strictly to the recommended dosing schedule to achieve optimal therapeutic outcomes and should
not adjust the dose or change the method of administration without consulting their physician.
Side Effects of Stelara
Headache.
Upper respiratory tract infections.
Fatigue.
Redness or pain at the injection site.
Skin itching.
Nausea.
Increased susceptibility to infections.
Contraindications
Stelara should not be used in patients with known hypersensitivity to ustekinumab or any of the product components.
It is also generally not recommended in cases of severe active infection unless deemed appropriate by a physician.
Patients should inform their healthcare provider about any history of chronic infections, tuberculosis, or immune
system disorders before starting treatment.
Alternatives to Stelara
Proper Use of Stelara
Patients should follow the treatment plan prescribed by their physician and avoid making any changes without medical
advice. Recommended laboratory tests and medical evaluations should be completed before and during treatment when
required.
It is important to monitor for signs of infection, such as fever or unusual symptoms, and report them promptly to a
healthcare professional.
Patients should also make every effort to avoid missing scheduled doses and should attend regular follow-up
appointments to assess treatment response and overall health status. The medication should never be shared with
another person, even if they have similar symptoms.
Storage Conditions
Store in a refrigerator at 2°C to 8°C (36°F to 46°F).
Do not freeze.
Keep in the original carton.
Protect from direct light.
Keep out of the reach of children.