Medicine Description xeloda 500 mg
xeloda 500 mg tablets is a medication that functions as an antimetabolite. It is converted in the body to 5-fluorouracil, which disrupts the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase. This action ultimately impedes the proliferation of cancer cells by interfering with the formation of nucleic acids necessary for cell division, thus leading to tumor cell death. Its selective toxicity towards rapidly dividing cells makes it particularly effective in various cancers.
Indications and Uses of xeloda 500 mg tablets
- Treatment of colon cancer
- Treatment of advanced or metastatic rectal cancer
- Management of breast cancer, particularly in cases where the disease has spread
Side Effects of xeloda 500 mg tablets
- Nausea and vomiting
- Diarrhea
- Fatigue
- Hand-foot syndrome (palmar-plantar erythrodysesthesia)
- Decreased blood cell counts (anemia, leukopenia, thrombocytopenia)
- Mouth sores (stomatitis)
- Loss of appetite
Storage and Handling
Store Xeloda tablets at room temperature, away from moisture and heat. Keep the medication in its original container and out of the reach of children. Do not use after the expiration date printed on the package.
Patient Advice and Precautions
Patients should stay well-hydrated while on therapy. Regular blood tests are essential to monitor for potential adverse effects, especially blood cell counts. Notify healthcare providers of any signs of infection, unusual bruising, or bleeding. It is advisable to avoid pregnancy during treatment and to discuss any current medications or supplements with a healthcare provider to prevent interactions.