Tibolone tablets are a unique oral medication specifically designed to address the changing health needs of postmenopausal women. These tablets contain a synthetic active ingredient called tibolone, which has the ability to mimic the effects of several natural female hormones, including estrogen, progesterone, and weak androgens. This unique property makes tibolone effective in managing a wide range of symptoms associated with declining hormone levels after menopause, in addition to providing significant protection against bone loss and osteoporosis. Tibolone is a valuable treatment option for women seeking a comprehensive solution to relieve menopausal symptoms, maintain bone health, and improve their overall quality of life.
The active ingredient in Tibolone tablets
The effectiveness of Tibolone tablets is based on the following active ingredient:
Tibolone: A synthetic steroid compound characterized by its triple pharmacological activity. After administration, tibolone is rapidly metabolized in the body into three main metabolites that contribute to its therapeutic effects. One of these metabolites has estrogenic activity, helping to alleviate the symptoms of estrogen deficiency. Another metabolite has progestogenic activity, while the third metabolite exhibits weak androgenic activity. This combination of hormonal activities gives tibolone a balanced effect on various tissues in the body, including bones, the reproductive system, and the brain.
Available Strengths
Tibolone tablets are typically available in the following main strengths:
Tibolone: 2.5 mg per tablet.
This strength is most commonly used to treat menopausal symptoms and prevent osteoporosis. Other strengths may be available in some markets depending on the manufacturer and local regulations, but 2.5 mg is the standard strength.
Indications for Use of Tibolone Tablets
Tibolone tablets are primarily used for the following conditions:
Management of Menopausal Symptoms: Tibolone provides effective relief from common symptoms associated with estrogen deficiency after menopause, such as hot flashes, night sweats, vaginal dryness, mood swings, and sleep disturbances.
Prevention of Osteoporosis in Postmenopausal Women at Risk of Fractures: Tibolone helps maintain bone density and reduce the risk of fractures due to osteoporosis, a condition in which bones become weak and brittle. It is an important option for women who cannot or do not want to take other osteoporosis treatments.