Human Albumin Ampoules are a sterile solution for intravenous injection containing a high concentration of human albumin, 200 grams per liter (20%). Albumin is a major protein found in blood plasma and performs multiple vital functions, including maintaining colloid osmotic pressure, which helps regulate fluid distribution between blood vessels and tissues, and transporting many important substances such as hormones, drugs, and ions. Intravenous human albumin is used to replace acute or chronic albumin deficiency in the blood, as well as to help restore plasma volume and maintain hemodynamic stability in a wide range of critical, life-threatening medical conditions.
Active ingredient in Human Albumin Ampoules
Human Albumin Ampoules contain the following main active ingredient:
Human Albumin: 200 g/L (20%). This albumin is obtained from donated human blood plasma and undergoes strict purification and sterilization processes to ensure its safety and efficacy for therapeutic use.
Available Concentrations
Human albumin ampoules are typically available in the following concentrations:
Human albumin: 20% (200 g/L).
Other concentrations of human albumin for intravenous injection, such as 5% (50 g/L), may be available to meet different therapeutic needs based on the patient's condition and the volume of fluid to be replaced. The treating physician determines the appropriate concentration based on a clinical assessment of each individual case.
Indications for Use of Human Albumin Ampoules
Human albumin ampoules are used in a variety of medical conditions requiring plasma volume support or replacement of albumin deficiency, including:
Acute Respiratory Distress Syndrome (ARDS): To help maintain plasma volume and reduce fluid accumulation in the lungs.
Nephrotic Syndrome: To replace albumin loss in the urine and help reduce edema.
Hemolytic Disease of the Newborn: In some cases, it helps stabilize blood circulation.
Ovarian Hyperstimulation Syndrome (OHSS): To manage plasma volume deficiency and prevent complications.
After paracentesis for removal of ascites: To replace albumin loss that may occur with the removal of large amounts of fluid.
Increasing plasma volume and maintaining cardiac output in cases of fluid loss, such as bleeding or severe burns (hypovolemia due to hemorrhage or severe burns): To restore blood volume and maintain cardiovascular function.
Hypoproteinemia: In cases where albumin deficiency is severe and contributes to edema or other complications.