Plavicard 75 mg tablets is a medication that functions as an antiplatelet agent. Its active ingredient, clopidogrel, selectively inhibits the P2Y12 subtype of adenosine diphosphate (ADP) receptors on the platelet surface. This inhibition prevents ADP-induced platelet activation and aggregation, thereby reducing the formation of blood clots. Clopidogrel undergoes metabolic activation in the liver, which converts it into its active form, leading to a prolonged antiplatelet effect. This mechanism is particularly beneficial in preventing thrombotic events in patients with atherosclerosis, as well as in those undergoing certain cardiac procedures.
Indications and Uses of Plavicard 75 mg tablets
- To reduce the risk of atherothrombotic events following recent myocardial infarction.
- To decrease the likelihood of stroke or myocardial infarction in patients with established peripheral arterial disease.
- For the prevention of stent thrombosis in patients undergoing percutaneous coronary intervention.
- To lower the risk of cardiovascular events in patients with acute coronary syndromes.
Side Effects of Plavicard 75 mg tablets
- Gastrointestinal bleeding
- Hemorrhagic events
- Rash
- Diarrhea
- Thrombocytopenia
- Allergic reactions such as itching
- Elevated liver enzymes
Storage and Handling
Store Plavicard 75 mg tablets at room temperature, away from moisture and heat, in a secure location out of the reach of children. Ensure the medication is kept in its original packaging until use.
Patient Advice and Precautions
Patients should be advised to report any unusual bleeding or bruising promptly. It is important to inform healthcare providers about all medications being taken to avoid potential drug interactions. Regular blood tests may be necessary to monitor platelet function and liver function. Patients should avoid activities that increase the risk of bleeding while on this medication.
Scientific Degree: pharmacist
Country: Egypt
Dr. Rawan Mosaad El-Saeed is a clinical pharmacist and medical content reviewer holding a Bachelor of Pharmacy degree from Horus University in Egypt. She has hands-on community pharmacy experience in providing medication therapy counseling, monitoring drug-drug interactions, and ensuring patient adherence to safe usage protocols. She specializes in authoring and fact-checking pharmaceutical guides and simplifying clinical pharmacology based on the latest evidence-based guidelines and internationally accredited references, dedicated to delivering accurate, reliable, and safe healthcare information for readers.
Published Date: 05 May 2025
Source 1 :
CLOPIDOGREL
you should ask your doctor before taking this medicine