Comparison of the difference between Lustral and Prozac tablets for treatment of depression

Both Lustral and Prozac are used to treat depression and various anxiety disorders, and both belong to the class of selective serotonin reuptake inhibitors (SSRIs). However, they differ in the active ingredient they contain, leading to differences in effectiveness, potential side effects, and drug interactions.

Lustral Tablets Ingredients

Lustral tablets contain the active ingredient sertraline. Sertraline is a selective serotonin reuptake inhibitor (SSRI) that works by blocking the reuptake of serotonin into neurons in the brain, increasing the amount of serotonin available for signal transmission between neurons. Serotonin plays an important role in regulating mood and anxiety.

Prozac Tablets Ingredients

Prozac tablets contain the active ingredient fluoxetine. Fluoxetine is also a selective serotonin reuptake inhibitor (SSRI) that works by a similar mechanism to sertraline to increase serotonin levels in the brain. Fluoxetine was one of the first SSRIs developed and has a long history of use.

Information about Lustral tablets

Drug class: Antidepressants

Drug classification: Selective serotonin reuptake inhibitors (SSRIs)

Pharmaceutical form: Coated tablets

Pharmaceutical family: Central nervous system drugs

Active ingredient: Sertraline

Information about Prozac tablets

Drug class: Antidepressants

Drug class: Selective serotonin reuptake inhibitors (SSRIs)

Pharmaceutical form: Tablets, capsules, solution

Pharmaceutical family: Central nervous system drugs

Active ingredient: Fluoxetine

Author Name: Dr. Rawan Mossad Elsaed

Scientific Degree: Pharmacist

Country: Egypt

Dr. Rawan Mosaad El-Saeed is a clinical pharmacist and medical content reviewer holding a Bachelor of Pharmacy degree from Horus University in Egypt. She has hands-on community pharmacy experience in providing medication therapy counseling, monitoring drug-drug interactions, and ensuring patient adherence to safe usage protocols. She specializes in authoring and fact-checking pharmaceutical guides and simplifying clinical pharmacology based on the latest evidence-based guidelines and internationally accredited references, dedicated to delivering accurate, reliable, and safe healthcare information for readers.

Published Date: 23 April 2025