Comparison the difference between Diamicron 60 MR and Amaryl for the treatment of type 2 diabetes

15 April 2025

    Both Diamicron 60 mg MR and Amaryl are effective medications used to treat type 2 diabetes. They belong to the sulfonylurea class and work to lower blood sugar levels by stimulating the pancreas to secrete more insulin. Although they are similar in their mechanism of action and therapeutic target, they differ in some important properties that may influence a doctor's choice of one over the other.

    Diamicron 60 mg MR Ingredients

    Diamicron 60 mg MR contains the active ingredient gliclazide. The suffix "MR" stands for "modified release," meaning that the medication is released slowly and steadily over a longer period of time. This helps maintain more stable levels of gliclazide in the blood and reduce fluctuations in blood sugar levels.

    Amaryl Ingredients

    Amaryl tablets contain the active ingredient glimepiride. Amaryl is available in different strengths, usually immediate-release or standard-release. Glimepiride also stimulates insulin secretion from beta cells in the pancreas, helping to lower high blood sugar levels.

    About Diamicron 60 mg MR

    Drug category: Diabetes medications

    Drug classification: Sulfonylureas

    Pharmaceutical form: Modified-release tablets

    Pharmaceutical family: Sulfonylureas

    Active ingredient: Gliclazide

    About Amaryl

    Drug category: Diabetes medications

    Drug classification: Sulfonylureas

    Pharmaceutical form: Tablets

    Pharmaceutical family: Sulfonylureas

    Active ingredient: Glimepiride

    Indications for Diamicron 60 mg MR tablets

    Diamicron 60 mg MR is used to treat type 2 diabetes in adults, especially when blood sugar control is not adequate with diet and exercise. Modified-release tablets help provide better blood sugar control throughout the day with a single dose.

    Indications for Amaryl tablets

    Amaryl is also used to treat type 2 diabetes in adults, with the aim of lowering high blood sugar levels. It is often prescribed as part of a treatment plan that includes diet and physical activity.

    Diamicron 60 mg MR and Amaryl Dosage

    The appropriate dose for each patient is determined individually by the doctor.

    Diamicron 60 mg MR: The usual starting dose is one tablet daily in the morning. The dose can be gradually adjusted according to the patient's response, with the maximum dose usually being two tablets daily.

    Amaryl: Doses available vary. The usual starting dose is 1 mg or 2 mg once daily, usually taken with breakfast or the first main meal. The dose can be gradually increased under the supervision of a doctor.


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