Medicine Description calcipoheal-cort 0.005%/0.05%
Calcipoheal-Cort Ointment is an advanced topical formulation that combines two active ingredients that work synergistically to treat certain chronic inflammatory skin conditions characterized by excessive skin cell proliferation and persistent inflammation. This ointment has a dual action: it inhibits excessive skin cell growth and reduces the thickness of affected skin patches, in addition to reducing inflammation, redness, itching, and discomfort associated with these skin conditions. This ointment is primarily used to treat plaque psoriasis, a chronic skin condition characterized by thick, red patches covered with silvery scales.
The active ingredient in Calcipoheal-Cort Ointment
Calcipoheal-Cort Ointment contains the following two active ingredients, which work synergistically to achieve the desired therapeutic effect:
Calcipotriol: 0.005% (w/w). It is a synthetic derivative of vitamin D3. Calcipotriol is characterized by its ability to regulate the growth and differentiation of skin cells. In the treatment of psoriasis, it helps slow the rate of skin cell growth and reduce their accumulation on the skin's surface, leading to a reduction in the thickness of psoriasis patches and an improvement in their appearance.
Betamethasone: 0.05% (w/w). It is a potent corticosteroid belonging to the class of highly potent corticosteroids. Betamethasone works by inhibiting the release of chemicals that cause inflammation in the skin, such as prostaglandins and cytokines. This leads to a reduction in the redness, swelling, itching, and pain associated with skin inflammations such as psoriasis.
Available Concentrations
Calcipohil-Cort Ointment is typically available in these specific, fixed concentrations of the two active ingredients to ensure a balanced and effective therapeutic formula with each application:
Calcipotriol: 50 micrograms per gram of ointment (0.005% w/w).
Betamethasone: 0.5 mg per gram of ointment (0.05% w/w) as betamethasone dipropionate. The ointment is usually applied in a thin layer to the affected area of skin once daily. Patients should carefully follow their physician's instructions regarding the amount of ointment to use and the duration of treatment. The duration of treatment may vary depending on the severity of the condition and the patient's response to treatment.
Indications for Use of Calcipoheal-Cort Ointment
Calcipoheal-Cort Ointment is primarily and effectively used to treat:
Plaque psoriasis: This ointment is a popular and effective treatment option for adults with plaque psoriasis, particularly those affecting limited areas of the body. The unique combination of calcipotriol and betamethasone works to address both the overgrowth of skin cells and the inflammation associated with psoriasis, resulting in a significant improvement in the symptoms and overall appearance of the affected skin.
Drug Interactions of Calcipoheal-Cort Ointment
Systemic absorption of both calcipotriol and betamethasone when applied topically at the recommended doses and applied to limited areas of the skin is relatively minimal. Therefore, the potential for significant drug interactions with other oral or injectable medications is considered low. However, patients should inform their physician of any other topical medications they are using on the same affected area at the same time as Calcipoheal-Cort Ointment to assess for any potential interactions, although these interactions are unlikely. The physician should also be informed of any other medications the patient is taking regularly, especially if they affect blood calcium levels (for calcipotriol) or if the patient is taking other oral or injectable corticosteroids (for betamethasone).
Calcipoheal-Cort Ointment Storage Conditions
Calcipoheal-Cort Ointment should be stored at room temperature, typically between 15 and 25°C (59 to 77°F), away from direct heat and light. The tube or container should be kept tightly closed after each use to prevent contamination or damage to the ointment. The medication should be kept out of the reach of children and pets in a secure place.
It is also important to check the expiry date printed on the package before using Calcibuheal-Cort ointment and dispose of any expired ointment properly according to local or pharmaceutical guidelines.