differences between janumet and gliptus plus for diabetes treatment of type 2 diabetes. Both are specifically used for patients who have difficulty achieving adequate control through a healthy diet and exercise. Therefore, both are excellent drug options because they contain the dual formulation of metformin in addition to sitagliptin or vildagliptin. This provides better control of blood sugar levels after eating with a low impact on weight and a lower risk of severe hypoglycemia. In this article, we will learn about the indications for use, appropriate doses, and the differences between them.
janumet ingredients
Contains the active ingredients:
- Metformin: This substance works to lower blood glucose levels by inhibiting glucose production by the liver, improving cell sensitivity to insulin, and slowing glucose absorption from the intestine.
- Sitagliptin: It belongs to a group of DPP-4 inhibitors that increase levels of incretin hormones. These hormones help the pancreas secrete more insulin only when blood sugar is high and reduce glucagon secretion by reducing glucose secretion from the liver during and after eating, leading to lower blood sugar levels, especially after meals.
gliptus Plus Ingredients
Contains the active ingredients:
- Vildagliptin: It belongs to a group of DPP-4 inhibitors. It works to ensure the prolonged presence of incretin hormones in the body by inhibiting the DPP-4 enzyme, thereby preventing the breakdown of both GLP-1 and GLP-1. It increases insulin secretion from the beta cells in the pancreas only when blood sugar is high, reduces glucagon secretion from the alpha cells in the pancreas, and also reduces liver production, improving blood sugar control both fasting and after meals.
- Metformin: This substance stimulates fat cells and muscles to respond to insulin and increase the entry of glucose to be used for energy production instead of remaining in the blood.