differences between tegretol and depakine chrono and their uses in treating various neurological and psychiatric disorders, especially epilepsy of various types and various convulsions. Each has its own pharmacological properties and mechanisms of action, making its use preferable in certain cases over others. Some work to stabilize mood by affecting ion channels in neurons, reducing manic episodes and mood swings in bipolar disorder. Others increase the level of inhibitory GABA and reduce the activity of sodium and calcium channels. Below, we will learn more about tegretol and depakine chrono , including their active ingredients, recommended dosages, and differences between them.
Ingredients of tegretol
It contains the active ingredient carbamazepine. This substance primarily works to inhibit excessive electrical activity in neurons by blocking voltage-dependent sodium channels and preventing these channels from opening for extended periods after each action potential. This reduces the frequency of rapid and abnormal nerve signals, especially in epileptic foci, and reduces the excessive excitability of neurons that causes nerve pain.
depakine chrono Ingredients
It contains the following active ingredients:
- Valproic acid works by increasing the inhibitory neurotransmitter GABA by inhibiting the enzyme responsible for breaking down GABA and increasing the activity of the enzyme responsible for its synthesis. This increases GABA concentration in the brain, reduces excessive neuronal activity, and reduces the frequency of successive neuronal firings, helping to reduce partial and generalized seizures.
- Sodium valproate is the soluble salt of valproic acid, which is converted to the valproate ion once it enters the body.