Comparison of the difference between Sifrol tablets and Cogentin ampoules for Parkinson's disease treatment

23 April 2025

    Both Sifrol and Cogentin are used to treat the symptoms of Parkinson's disease, but they belong to two different classes of medications that work by different mechanisms to address the dopamine deficiency in the brain associated with the disease. Additionally, Cogentin is also available in the form of injection ampoules, which expands its use in certain conditions.

    Ingredients of Sifrol Tablets

    Sifrol tablets contain the active ingredient pramipexole. Pramipexole is a dopamine agonist, meaning it mimics the effect of dopamine in the brain by binding to and activating dopamine receptors. It helps relieve symptoms of Parkinson's disease such as tremor, rigidity, slowness of movement, and difficulty with balance. Sifrol is available in the form of tablets for oral administration.

    Ingredients of Cogentin Ampoules

    Cogentin Ampoules contain the active ingredient benztropine mesylate. Benztropine is an anticholinergic drug that works by blocking the action of a chemical called acetylcholine in the brain. In Parkinson's disease, an imbalance occurs between dopamine and acetylcholine. Blocking acetylcholine can help relieve some symptoms, especially tremors and rigidity. Cogentin is available as tablets for swallowing and ampoules for intramuscular or intravenous injection.

    About Sifrol Tablets

    Drug Class: Dopamine Agonists

    Drug Classification: Non-Ergot

    Pharmaceutical Form: Tablets

    Pharmacological Family: Central Nervous System Drugs, Drugs for the Treatment of Parkinson's Disease

    Active Ingredient: Pramipexole

    About Cogentin Ampoules

    Drug Class: Anticholinergic

    Drug Classification: Tertiary Amine

    Pharmaceutical Form: Ampoules for Injection (also available as tablets)

    Pharmacological Family: Central Nervous System Drugs, Drugs for the Treatment of Parkinson's Disease

    Active Ingredient: Benztropine Mesylate


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