Ciprofloxacin tablets are a powerful and effective second-generation fluoroquinolone antibiotic. These coated tablets contain a high dose of the active ingredient ciprofloxacin (750 mg) in each tablet. Ciprofloxacin's broad spectrum of antibacterial activity makes it an important treatment option for a variety of bacterial infections that may be resistant to other antibiotics and affect various body systems.
The active ingredient in Ciprofloxacin tablets
The therapeutic efficacy of Ciprofloxacin tablets depends primarily on the presence of the following active ingredient in precise and specific concentrations:
Ciprofloxacin: Available in a concentration of 750 mg per tablet, it is usually ciprofloxacin hydrochloride, a stable salt of the drug that ensures good oral absorption. Ciprofloxacin is a broad-spectrum antibiotic that is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as some other microorganisms.
Mechanism of Action of Ciprofloxacin Tablets
Ciprofloxacin works by targeting and inhibiting two vital enzymes that play a crucial role in DNA replication, repair, and chromosome segregation within bacterial cells:
DNA gyrase: An enzyme responsible for unwinding bacterial DNA to facilitate replication and transcription.
Topoisomerase IV: An enzyme involved in separating bacterial chromosomes after replication to ensure proper cell division.
By inhibiting these two enzymes, ciprofloxacin disrupts the vital processes necessary for bacterial growth and reproduction, leading to cessation of growth and eventual death. This unique mechanism of action makes ciprofloxacin effective against many bacterial strains that may be resistant to other antibiotics that work in different ways.
Indications for Use of Ciprofloxacin Tablets
Ciprofloxacin 750 mg tablets are used to treat a wide range of serious and complex bacterial infections affecting various body systems, including:
Complicated urinary tract infections (CUTIs): including acute pyelonephritis.
Lower respiratory tract infections: such as hospital-acquired pneumonia and pneumonia in patients with cystic fibrosis.
Complicated skin and soft tissue infections: such as infected diabetic foot infections and deep wound infections.
Bone and joint infections: such as osteomyelitis and septic arthritis.
Severe gastrointestinal infections: such as acute infectious diarrhea caused by certain bacteria.
Certain types of serious systemic infections: such as bacteremia and pelvic inflammatory disease.
Treatment and prevention of anthrax after exposure.
Ciprofloxacin tablets should only be used to treat bacterial infections diagnosed by a physician and after performing sensitivity tests to determine the response of the bacteria causing the infection to this antibiotic.
How to Use Ciprofloxacin Tablets
Ciprofloxacin tablets should be taken orally with a sufficient amount of water. The tablets can be taken with or without food, but it is preferable to take them on an empty stomach (one hour before or two hours after meals) to ensure optimal absorption and maximum effectiveness. The exact dosage and duration of treatment depend on the type and severity of the infection, its location, the patient's general condition, kidney and liver function, and the treating physician's recommendations. General guidelines for use for adults are usually one tablet (750 mg) every 12 hours. It is extremely important to follow your doctor's instructions carefully regarding dosage, timing, and duration of treatment. Do not exceed the recommended dose or stop taking the medication before the prescribed period is over, even if your symptoms improve. Stopping treatment prematurely may lead to recurrence of the infection and the emergence of antibiotic-resistant bacterial strains.